Article
The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth.
The Plant cell - 1 Feb 2007
Fleury Delphine, Himanen Kristiina, Cnops Gerda, Nelissen Hilde, Boccardi Tommaso Matteo, Maere Steven, Beemster Gerrit T S, Neyt Pia, Anami Sylvester, Robles Pedro, Micol José Luis, Inzé Dirk, Van Lijsebettens Mieke
Abstract excerpt
Chromatin modification and transcriptional activation are novel roles for E3 ubiquitin ligase proteins that have been mainly associated with ubiquitin-dependent proteolysis. We identified HISTONE MONOUBIQUITINATION1 (HUB1) (and its homolog HUB2) in Arabidopsis thaliana as RING E3 ligase proteins with a function in organ growth. We show that HUB1 is a functional homolog of the human and yeast BRE1 proteins because...
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