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Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivo

1 Jan 2012

Abstract excerpt

Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Previous in vitro experiments identified a stimulatory effect of pantothenate on migration, proliferation and gene regulation in cultured human dermal fibroblasts. To correlate these in vitro findings with the more complex in vivo situation of wound healing, a clinical trial was performed in which the...

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PMID: 22759998
DOI: 10.1159/000341144

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