Article
Guided evolution of in silico microbial populations in complex environments accelerates evolutionary rates through a step-wise adaptation.
BMC bioinformatics - 25 Jun 2012
Mozhayskiy Vadim, Tagkopoulos Ilias
Abstract excerpt
BACKGROUND: During their lifetime, microbes are exposed to environmental variations, each with its distinct spatio-temporal dynamics. Microbial communities display a remarkable degree of phenotypic plasticity, and highly-fit individuals emerge quite rapidly during microbial adaptation to novel environments. However, there exists a high variability when it comes to adaptation potential, and while adaptation occurs...
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