Article
Tumor response and toxicity of neoadjuvant erlotinib in patients with early-stage non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Aug 2012
Schaake Eva E, Kappers Ingrid, Codrington Henk E, Valdés Olmos Renato A, Teertstra Hendrik J, van Pel Renée, Burgers Jacobus A, van Tinteren Harm, Klomp Houke M
Abstract excerpt
PURPOSE: The development of targeted therapy has introduced new options to improve treatment outcome in selected patients. The objective of this prospective study was to investigate the safety of preoperative erlotinib treatment and the (in vivo) response in patients with early-stage resectable non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: This study was designed as an open-label phase II trial,...
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