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Article

Integration of genome-wide expression and methylation data: relevance to aging and Alzheimer's disease.

Neurotoxicology - 1 Dec 2012

Alashwal Hany, Dosunmu Remi, Zawia Nasser H

Abstract excerpt

The progressive and latent nature of neurodegenerative diseases, such as Alzheimer's disease (AD) indicates the role of epigenetic modification in disease susceptibility. Previous studies from our lab show that developmental exposure to lead (Pb) perturbs the expression of AD-associated proteins. In order to better understand the role of DNA methylation as an epigenetic modifications mechanism in gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22743688
DOI: 10.1016/j.neuro.2012.06.008
PMCID: PMC3469774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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