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Article

Role of IS <i>Kpn7</i> and Deletions in <i>bla</i> <sub>KPC</sub> Gene Expression

27 Jun 2012

Abstract excerpt

The carbapenemase-encoding bla(KPC) gene, which is rapidly spreading in Gram-negative rods, is located on a Tn3-based transposon, Tn4401, which carries a polymorphic region giving rise to five isoforms (a, b, c, d, and e) that is located immediately upstream of the bla(KPC) gene and thus likely involved in its expression. Using 5' rapid amplification of cDNA ends (5'RACE), we identified three potential promoter...

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PMID: 22733068
DOI: 10.1128/aac.00334-12

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