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Article

ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p.

Nature cell biology - 24 Jun 2012

Chen Shuliang, Novick Peter, Ferro-Novick Susan

Abstract excerpt

Although studies on endoplasmic reticulum (ER) structure and dynamics have focused on the ER tubule-forming proteins (reticulons and DP1/Yop1p) and the tubule fusion protein atlastin, nothing is known about the proteins and processes that act to counterbalance this machinery. Here we show that Lnp1p, a member of the conserved Lunapark family, plays a role in ER network formation. Lnp1p binds to the reticulons and...

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PMID: 22729086
DOI: 10.1038/ncb2523
PMCID: PMC3389217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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