Article
Genomic analysis of between-cow variation in dermal fibroblast response to lipopolysaccharide.
Journal of dairy science - 1 Jul 2012
Kandasamy S, Kerr D E
Abstract excerpt
The innate immune response plays a major role in defense against mastitis-causing pathogens. Identification of existing variation in innate immune signaling among cows and the underlying molecular causes for the variation may help in design of new mastitis control strategies. The dermal fibroblast has been used as a model cell type to explore between-cow variation in the ability of cells to produce IL-8 in...
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