Article
Genotyping of Brucella species using clade specific SNPs.
BMC microbiology - 19 Jun 2012
Foster Jeffrey T, Price Lance B, Beckstrom-Sternberg Stephen M, Pearson Talima, Brown William D, Kiesling Danika M, Allen Christina A, Liu Cindy M, Beckstrom-Sternberg James, Roberto Frank F, Keim Paul
Abstract excerpt
BACKGROUND: Brucellosis is a worldwide disease of mammals caused by Alphaproteobacteria in the genus Brucella. The genus is genetically monomorphic, requiring extensive genotyping to differentiate isolates. We utilized two different genotyping strategies to characterize isolates. First, we developed a microarray-based assay based on 1000 single nucleotide polymorphisms (SNPs) that were identified from whole...
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