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Meta analysis of angiotensin-converting enzyme I/D polymorphism as a risk factor for preeclampsia in Chinese women.

Genetics and molecular research : GMR - 13 Aug 2012

Zhong W G, Wang Y, Zhu H, Zhao X

Abstract excerpt

Preeclampsia affects 3-8% of pregnancies and is a major cause of maternal and perinatal morbidity and mortality worldwide. Inappropriate activation of the renin-angiotensin system may play a role in the development of preeclampsia. An insertion/deletion polymorphism in the angiotensin-converting enzyme gene (ACE-I/D) has been associated with differences in ACE activity. However, there are controversies in...

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Identifiers

PMID: 22653650
DOI: 10.4238/2012.May.21.1

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ACE

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