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Higher clusterin immunolabeling and sperm DNA damage levels in hypertensive men compared with controls

30 May 2012

Abstract excerpt

BACKGROUND: Clusterin, a heterodimeric glycoprotein found at several sites in the human male reproductive tract, could be a marker of morphologically abnormal spermatozoa, while TUNEL positivity indicates DNA fragmentation. Metabolic disorders such as diabetes mellitus and obesity may compromise sperm quality and fertility of men; however, little evidence specifically links hypertension with the impairment of...

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PMID: 22647452
DOI: 10.1093/humrep/des173

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