Article
Potential effect of smoking on semen quality through DNA damage and the downregulation of Chk1 in sperm
20 May 2016
Abstract excerpt
Previous studies have found that smoking is associated with decreased male fertility via altering the quality of semen. However, the mechanism by which cigarette smoking affects semen quality remains to be fully elucidated. Heavy smoking-induced DNA damage has been reported to correlate with abnormal spermatozoa and male infertility. It has been reported that, in response to DNA damage, activation of the...
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