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Article

Age- and gender-specific effects on NRAMP1 gene polymorphisms and risk of the development of active tuberculosis in Tunisian populations.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2012

Ben-Selma Walid, Harizi Hedi, Letaief Mahmoud, Boukadida Jalel

Abstract excerpt

BACKGROUND: Studies that have assessed NRAMP1 polymorphisms and their association with susceptibility to tuberculosis (TB) in humans have yielded conflicting results. In this study, we evaluated the association between NRAMP1 gene polymorphisms and the risk of the development of active TB in Tunisian populations. METHODS: The distribution of 3'-UTR and D543N polymorphisms in 223 TB patients (168 patients with...

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PMID: 22609013
DOI: 10.1016/j.ijid.2011.11.016

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