Article
Dopamine receptors D1 and D2 are related to observed maternal behavior.
Genes, brain, and behavior - 1 Aug 2012
Mileva-Seitz V, Fleming A S, Meaney M J, Mastroianni A, Sinnwell J P, Steiner M, Atkinson L, Levitan R D, Matthews S G, Kennedy J L, Sokolowski M B
Abstract excerpt
The dopamine pathway and especially the dopamine receptors 1 and 2 (DRD1 and DRD2) are implicated in the regulation of mothering in rats. Evidence for this in humans is lacking. Here, we show that genetic variation in both DRD1 and DRD2 genes in a sample of 187 Caucasian mothers predicts variation in distinct maternal behaviors during a 30-min mother-infant interaction at 6 months postpartum. Two DRD1...
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