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Article

Nonpathological Extracellular Amyloid Is Present during Normal Epididymal Sperm Maturation

3 May 2012

Abstract excerpt

Amyloids are aggregated proteins characterized by a specific cross-β-sheet structure and are typically associated with neurodegenerative diseases including Alzheimer's disease. Recently, however, several nonpathological amyloids have been found in intracellular organelles of normal mammalian tissues suggesting that amyloid may also carry out biological functions. We previously have shown that the epididymal...

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PMID: 22570708
DOI: 10.1371/journal.pone.0036394

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