Article
Development of robust discriminant equations for assessing subtypes of glioblastoma biopsies.
British journal of cancer - 22 May 2012
Castells X, Acebes J J, Majós C, Boluda S, Julià-Sapé M, Candiota A P, Ariño J, Barceló A, Arús C
Abstract excerpt
BACKGROUND: In the preceding decade, various studies on glioblastoma (Gb) demonstrated that signatures obtained from gene expression microarrays correlate better with survival than with histopathological classification. However, there is not a universal consensus formula to predict patient survival. METHODS: We developed a gene signature using the expression profile of 47 Gbs through an unsupervised procedure and...
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