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Article

Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene.

Fish & shellfish immunology - 1 Jun 2012

Lv Jianjian, Huang Rong, Li Huaying, Luo Daji, Liao Lanjie, Zhu Zuoyan, Wang Yaping

Abstract excerpt

Toll-like receptor 22 (TLR22) is a fish-specific TLR which recognizes double-strand (ds) RNA and participates in the innate immune response through the Toll-IL-1R homology domain-containing adaptor protein 1 (TICAM-1). To further investigate how the innate immune system of teleosts responds to viral infections, we cloned the full-length cDNA sequence of grass carp (Ctenopharyngodon idella) TLR22 (CiTLR22). The...

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PMID: 22554574
DOI: 10.1016/j.fsi.2012.02.024

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