Article
Indicators of therapeutic effect in FIT-06, a Phase II trial of a DNA vaccine, GTU(®)-Multi-HIVB, in untreated HIV-1 infected subjects.
Vaccine - 8 Jun 2012
Vardas Eftyhia, Stanescu Ioana, Leinonen Mika, Ellefsen Kim, Pantaleo Giuseppe, Valtavaara Minna, Ustav Mart, Reijonen Kalevi
Abstract excerpt
BACKGROUND: Combination highly active antiretroviral therapy (HAART) has significantly decreased HIV-1 related morbidity and mortality globally transforming HIV into a controllable condition. HAART has a number of limitations though, including limited access in resource constrained countries, which have driven the search for simpler, affordable HIV-1 treatment modalities. Therapeutic HIV-1 vaccines aim to provide...
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