Article
Frequent polymorphisms of FSH receptor do not influence antral follicle responsiveness to follicle-stimulating hormone administration as assessed by the Follicular Output RaTe (FORT).
Journal of assisted reproduction and genetics - 1 Jul 2012
Genro Vanessa Krebs, Matte Ursula, De Conto Emily, Cunha-Filho João Sabino, Fanchin Renato
Abstract excerpt
PURPOSE: To verify whether carriers of common single-nucleotide polymorphisms (SNPs) of the FSH receptor (FSHR) show reduced responsiveness of antral follicles to FSH administration as assessed by the FORT. METHODS: We performed a prospective study in a university hospital. Study population consisted of 124 Caucasian IVF-ET candidates. FSHR 307Ala and 680Ser variants were analyzed in haplotypes and as separated...
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