Article
Transcription factor 7-like 2 gene polymorphisms and gestational diabetes mellitus.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Sept 2012
Klein Katharina, Haslinger Peter, Bancher-Todesca Dagmar, Leipold Heinz, Knöfler Martin, Handisurya Ammon, Kautzky-Willer Alexandra, Worda Christof
Abstract excerpt
OBJECTIVE: Transcription factor 7-like 2 (TCF7L2) gene polymorphisms were shown to be associated with insulin resistance. We examined two single nucleotide exchanges in this gene in women with gestational diabetes mellitus (GDM) and in women with normal glucose tolerance. METHODS: A total of 1800 unselected women were prospectively screened for GDM by oral glucose tolerance test (OGTT) between 24 and 28 weeks of...
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