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Article

Molecular characterization of rotavirus strains detected during a clinical trial of a human rotavirus vaccine in Blantyre, Malawi.

Vaccine - 27 Apr 2012

Nakagomi Toyoko, Nakagomi Osamu, Dove Winifred, Doan Yen Hai, Witte Desiree, Ngwira Bagrey, Todd Stacy, Duncan Steele A, Neuzil Kathleen M, Cunliffe Nigel A

Abstract excerpt

The human, G1P[8] rotavirus vaccine (Rotarix™) significantly reduced severe rotavirus gastroenteritis episodes in a clinical trial in South Africa and Malawi, but vaccine efficacy was lower in Malawi (49.5%) than reported in South Africa (76.9%) and elsewhere. The aim of this study was to examine the molecular relationships of circulating wild-type rotaviruses detected during the clinical trial in Malawi to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22520123
DOI: 10.1016/j.vaccine.2011.09.119
PMCID: PMC3982048

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