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Article

Comparison of the Abbott RealTime High-Risk Human Papillomavirus (HPV), Roche Cobas HPV, and Hybrid Capture 2 assays to direct sequencing and genotyping of HPV DNA.

Journal of clinical microbiology - 1 Jul 2012

Park Yongjung, Lee Eunhee, Choi Jonghyeon, Jeong Seri, Kim Hyon-Suk

Abstract excerpt

Infection with high-risk (HR) human papillomavirus (HPV) genotypes is an important risk factor for cervical cancers. We evaluated the clinical performances of two new real-time PCR assays for detecting HR HPVs compared to that of the Hybrid Capture 2 test (HC2). A total of 356 cervical swab specimens, which had been examined for cervical cytology, were assayed by Abbott RealTime HR and Roche Cobas HPV as well as...

Topics

Cervix Uteri
DNA, Viral
Female
Genotype
Humans
Molecular Diagnostic Techniques
Nucleic Acid Hybridization
Papillomaviridae
Papillomavirus Infections
Real-Time Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sensitivity and Specificity

Sequence Analysis, DNA

Virology

Source

Open in PubMed Open full text

Identifiers

PMID: 22518863
DOI: 10.1128/JCM.00337-12
PMCID: PMC3405569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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