Article
Gemifloxacin can partially overcome quinolone resistance of H. pylori with gyrA mutation in Taiwan.
Helicobacter - 1 Jun 2012
Chang Wei-Lun, Kao Cheng-Yen, Wu Chung-Tai, Huang Ay-Huey, Wu Jiunn-Jong, Yang Hsiao-Bai, Cheng Hsiu-Chi, Sheu Bor-Shyang
Abstract excerpt
BACKGROUNDS: The levofloxacin resistance caused by gyrA gene mutation is rising rapidly to limit wide application for Helicobacter pylori eradication. We investigated whether gemifloxacin has a superior antimicrobial activity to levofloxacin against H. pylori. MATERIALS AND METHODS: Forty-four consecutive clinical H. pylori isolates with levofloxacin resistance and 80 randomly selected levofloxacin-sensitive...
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