The introduction of arrays in prenatal diagnosis: A special challenge

Abstract excerpt

Genome-wide arrays are rapidly replacing conventional karyotyping in postnatal cytogenetic diagnostics and there is a growing request for arrays in the prenatal setting. Several studies have documented 1-3% additional abnormal findings in prenatal diagnosis with arrays compared to conventional karyotyping. A recent meta-analysis demonstrated that 5.2% extra diagnoses can be expected in fetuses with ultrasound...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fetal and Pediatric Neurological Disorders
• Share to Genomic variations and chromosomal abnormalities
• Share to Prenatal Screening and Diagnostics