Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection

Abstract excerpt

Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target for vaccine delivery is the skin. Recent studies have demonstrated improved immune responses after transdermal...

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