Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A premature stop codon in the ADAMTS2 gene is likely to be responsible for dermatosparaxis in Dorper sheep.

Animal genetics - 1 Aug 2012

Zhou H, Hickford J G H, Fang Q

Abstract excerpt

We have used polymerase chain reaction-single-strand conformational polymorphism analysis to investigate variation in exon 2 of the ADAM metalloproteinase with thrombospondin type I motif, 2 (ADAMTS2) gene in 598 sheep, including three white Dorper lambs that had a pathology consistent with dermatosparaxis. Four sequence variants (A, B, C and D) were identified at this exon, with the lambs having the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to Codon, Nonsense
Share to Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single-Stranded Conformational

Share to Sheep Diseases

Share to Sheep, Domestic

Share to Skin Diseases, Genetic

Source

Identifiers

PMID: 22497338
DOI: 10.1111/j.1365-2052.2011.02275.x

Genes

ADAMTS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

A premature stop codon in the ADAMTS2 gene is likely to be responsible for dermatosparaxis in Dorper sheep.PMID 22497338Read ↗

Identification of an ADAMTS2 frameshift variant in a cat family with Ehlers-Danlos syndrome.Semantic proximity Read ↗

Identification of single nucleotide polymorphisms in sheep Mx genes: A premature stop codon abolishes Mx2 protein expression but did not affect fertility and early animal development.Semantic proximity Read ↗

The occurrence of dermatosparaxis in a commercial Drakensberger cattle herd in South Africa.Semantic proximity Read ↗

Truncated gamma-glutamyl carboxylase in rambouillet sheep.Semantic proximity Read ↗

Novel Homozygous ADAMTS2 Variants and Associated Disease Phenotypes in Dogs with Dermatosparactic Ehlers-Danlos Syndrome.Semantic proximity Read ↗

Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type.Semantic proximity Read ↗

Search for variation in the ovine KAP7-1 and KAP8-1 genes using polymerase chain reaction-single-stranded conformational polymorphism screening.Semantic proximity Read ↗

Molecular cloning, sequence characteristics, and polymorphism analyses of the tyrosinase-related protein 2 / DOPAchrome tautomerase gene of black-boned sheep (Ovis aries).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.