[Roles of axonal transport affected by K141N mutant HSP22 in the pathogenesis of CMT2L].

doi:10.3760/cma.j.issn.00376-2491-2012.07.017

Article

[Roles of axonal transport affected by K141N mutant HSP22 in the pathogenesis of CMT2L].

Zhonghua yi xue za zhi - 21 Feb 2012

Zhang Fu-Feng, Lu Xiao-Qin, Zhou Ya-Fang, Shen Lu, Jiang Hong, Yan Xin-Xiang, Tang Bei-Sha

Abstract excerpt

OBJECTIVE: To compare the axonal transport of wild-type (WT) and K141N mutant HSP22 in transfected primary cultured cortical neurons. METHODS: The plasmid (pCAGGS-HA-wtHSP22 or pCAGGS-HA-K141NHSP22) with WT or K141N mutant HSP22 gene and a GFP-expressing plasmid (pEGFP-N1) were co-transfected res...

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[Roles of axonal transport affected by K141N mutant HSP22 in the pathogenesis of CMT2L].

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