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Article

Changes in DNA methylation and transgenerational mobilization of a transposable element (mPing) by the topoisomerase II inhibitor, etoposide, in rice.

BMC plant biology - 9 Apr 2012

Yang Xuejiao, Yu Yingjie, Jiang Lily, Lin Xiuyun, Zhang Chunyu, Ou Xiufang, Osabe Kenji, Liu Bao

Abstract excerpt

BACKGROUND: Etoposide (epipodophyllotoxin) is a chemical commonly used as an anti-cancer drug which inhibits DNA synthesis by blocking topoisomerase II activity. Previous studies in animal cells have demonstrated that etoposide constitutes a genotoxic stress which may induce genomic instability i...

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PMID: 22482475
DOI: 10.1186/1471-2229-12-48
PMCID: PMC3480845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22482475-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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