Article
[Genetics of pheochromocytoma].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen - 1 Jun 2012
Bausch B, Malinoc A, Maruschke L, Offergeld C, Gläsker S, Rischke H C, Brauckhoff M, Boedeker C C, Neumann H P H
Abstract excerpt
About one third of all patients with a pheochromocytoma are carriers of germ line mutations of 1 of the 10 susceptibility genes. Thus, these patients can be diagnosed and classified with specific tumor syndromes. This group is composed of the entities of multiple endocrine neoplasia type 2 (MEN2) due to mutations in the RET gene, von Hippel-Lindau disease (VHL, VHL gene), the paraganglioma syndromes types 1-4...
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