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Article

The effect of GM-CSF on development and aneuploidy in murine blastocysts

29 Mar 2012

Abstract excerpt

BACKGROUND: Growth factors and cytokines are present in small quantities in the oviduct and uterus and some are synthesized by the growing embryo. Granulocytes-macrophage colony-stimulating factor (GM-CSF) is known as an important regulator, which enhances cell proliferation and reduces apoptosis in developing blastocysts, during normal fetal and placental development. The purpose of this study is to investigate...

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PMID: 22461004
DOI: 10.1093/humrep/des108

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