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Article

Calpain 3 is important for muscle regeneration: evidence from patients with limb girdle muscular dystrophies.

BMC musculoskeletal disorders - 23 Mar 2012

Hauerslev Simon, Sveen Marie-Louise, Duno Morten, Angelini Corrado, Vissing John, Krag Thomas O

Abstract excerpt

BACKGROUND: Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of t...

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Source

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Identifiers

PMID: 22443334
DOI: 10.1186/1471-2474-13-43
PMCID: PMC3338386

Genes

CAPN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22443334-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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