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Article

Extensive genetic diversity within the Dutch clinical Cryptococcus neoformans population.

Journal of clinical microbiology - 1 Jun 2012

Hagen Ferry, Illnait-Zaragozí María-Teresa, Meis Jacques F, Chew William H M, Curfs-Breuker Ilse, Mouton Johan W, Hoepelman Andy I M, Spanjaard Lodewijk, Verweij Paul E, Kampinga Greetje A, Kuijper Ed J, Boekhout Teun, Klaassen Corné H W

Abstract excerpt

A set of 300 Dutch Cryptococcus neoformans isolates, obtained from 237 patients during 1977 to 2007, was investigated by determining the mating type, serotype, and AFLP and microsatellite genotype and susceptibility to seven antifungal compounds. Almost half of the studied cases were from HIV-infected patients, followed by a patient group of individuals with other underlying diseases and immunocompetent...

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Identifiers

PMID: 22442325
DOI: 10.1128/JCM.06750-11
PMCID: PMC3372159

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