Article
Personal omics profiling reveals dynamic molecular and medical phenotypes.
Cell - 16 Mar 2012
Chen Rui, Mias George I, Li-Pook-Than Jennifer, Jiang Lihua, Lam Hugo Y K, Chen Rong, Miriami Elana, Karczewski Konrad J, Hariharan Manoj, Dewey Frederick E, Cheng Yong, Clark Michael J, Im Hogune, Habegger Lukas, Balasubramanian Suganthi, O'Huallachain Maeve, Dudley Joel T, Hillenmeyer Sara, Haraksingh Rajini, Sharon Donald, Euskirchen Ghia, Lacroute Phil, Bettinger Keith, Boyle Alan P, Kasowski Maya, Grubert Fabian, Seki Scott, Garcia Marco, Whirl-Carrillo Michelle, Gallardo Mercedes, Blasco Maria A, Greenberg Peter L, Snyder Phyllis, Klein Teri E, Altman Russ B, Butte Atul J, Ashley Euan A, Gerstein Mark, Nadeau Kari C, Tang Hua, Snyder Michael
Abstract excerpt
Personalized medicine is expected to benefit from combining genomic information with regular monitoring of physiological states by multiple high-throughput methods. Here, we present an integrative personal omics profile (iPOP), an analysis that combines genomic, transcriptomic, proteomic, metabolomic, and autoantibody profiles from a single individual over a 14 month period. Our iPOP analysis revealed various...
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