Article
Embryonic stem cells for severe heart failure: why and how?
Journal of cardiovascular translational research - 1 Oct 2012
Menasché Philippe
Abstract excerpt
The experience accumulated in cardiac cell therapy suggests that regeneration of extensively necrotic myocardial areas is unlikely to be achieved by the sole paracrine effects of the grafted cells but rather requires the conversion of these cells into cardiomyocytes featuring the capacity to substitute for those which have been irreversibly lost. In this setting, the use of human pluripotent embryonic stem cells...
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