Article
Reverse breeding in Arabidopsis thaliana generates homozygous parental lines from a heterozygous plant.
Nature genetics - 11 Mar 2012
Wijnker Erik, van Dun Kees, de Snoo C Bastiaan, Lelivelt Cilia L C, Keurentjes Joost J B, Naharudin Nazatul Shima, Ravi Maruthachalam, Chan Simon W L, de Jong Hans, Dirks Rob
Abstract excerpt
Traditionally, hybrid seeds are produced by crossing selected inbred lines. Here we provide a proof of concept for reverse breeding, a new approach that simplifies meiosis such that homozygous parental lines can be generated from a vigorous hybrid individual. We silenced DMC1, which encodes the m...
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