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Effects of Cholesterol on Helicobacter pylori Growth and Virulence Properties In Vitro

8 Mar 2012

Abstract excerpt

BACKGROUND: Colonization of the gastric mucosa by Helicobacter pylori is often associated with chronic gastric pathologies in humans. Development of disease correlates with the presence of distinct bacterial pathogenicity factors, such as the cag type IV secretion system (cag-T4SS), the vacuolating cytotoxin (VacA), or the ability of the bacteria to acquire and incorporate cholesterol from human tissue. MATERIALS...

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PMID: 22404444
DOI: 10.1111/j.1523-5378.2011.00926.x

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