Article
Non-invasive genotyping of Helicobacter pylori cagA, vacA, and hopQ from asymptomatic children.
Helicobacter - 1 Apr 2012
Sicinschi Liviu A, Correa Pelayo, Bravo Luis E, Peek Richard M, Wilson Keith T, Loh John T, Yepez Maria C, Gold Benjamin D, Thompson Dexter T, Cover Timothy L, Schneider Barbara G
Abstract excerpt
BACKGROUND: Helicobacter pylori infection is usually acquired in childhood, but little is known about its natural history in asymptomatic children, primarily due to the paucity of non-invasive diagnostic methods. H. pylori strains harboring cagA and specific alleles of hopQ and vacA are associated with increased risk for gastric cancer. Many studies of H. pylori virulence markers in children have the bias that...
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