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Article

High circulating folate and vitamin B-12 concentrations in women during pregnancy are associated with increased prevalence of atopic dermatitis in their offspring.

The Journal of nutrition - 1 Apr 2012

Kiefte-de Jong Jessica C, Timmermans Sarah, Jaddoe Vincent W V, Hofman Albert, Tiemeier Henning, Steegers Eric A, de Jongste Johan C, Moll Henriette A

Abstract excerpt

Recent studies suggest that in utero exposure of methyl donors influences programming of the fetal immune system in favor of development of allergic disease. The aim of this study was to assess whether the MTHFR C677T polymorphism, folic acid supplementation, and circulating folate and vitamin B-12 concentrations during pregnancy were associated with wheezing, shortness of breath, and atopic dermatitis in...

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Source

Identifiers

PMID: 22399526
DOI: 10.3945/jn.111.154948

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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High circulating folate and vitamin B-12 concentrations in women during pregnancy are associated with increased prevalence of atopic dermatitis in their offspring.PMID 22399526Read ↗

The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population‐based, longitudinal birth cohortSemantic proximity Read ↗

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