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Genome-Wide microRNA Expression Profiling in Human Spermatozoa and Its Relation to Sperm Quality

4 Jan 2025

Abstract excerpt

Background: Sperm samples are separated into bad and good quality samples in function of their phenotype, but this does not indicate their genetic quality. Methods: Here, we used GeneChip miRNA arrays to analyze microRNA expression in ten semen samples selected based on high-magnification morphology (score 6 vs. score 0) to identify miRNAs linked to sperm phenotype. Results: We found 86 upregulated and 21...

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PMID: 39858600
DOI: 10.3390/genes16010053

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