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Article

Plasma levels of PCSK9 and phenotypic variability in familial hypercholesterolemia.

Journal of lipid research - 1 May 2012

Huijgen R, Fouchier S W, Denoun M, Hutten B A, Vissers M N, Lambert G, Kastelein J J P

Abstract excerpt

The extent of hypercholesterolemia varies considerably in patients with familial hypercholesterolemia (FH). We hypothesized that the variability of the FH phenotype might be partly explained by variation in proprotein convertase subtilisin kexin type 9 (PCSK9) activity. Individuals between 18 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22375030
DOI: 10.1194/jlr.P023994
PMCID: PMC3329397

Genes

PCSK9
APOB
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22375030-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Plasma levels of PCSK9 and phenotypic variability in familial hypercholesterolemia.PMID 22375030Read ↗

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