Article
The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma.
PloS one - 1 Jan 2012
O'Mahony Fiach C, Faratian Dana, Varley James, Nanda Jyoti, Theodoulou Marianna, Riddick Antony C P, Harrison David J, Stewart Grant D
Abstract excerpt
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) has recently been implicated in the initiation and progression of renal cell carcinoma (RCC). Some mRNA gene expression studies have suggested a link between the EMT phenotype and poorer clinical outcome from RCC. This study evaluated expression of EMT-associated proteins in RCC using in situ automated quantitative analysis immunofluorescence (AQUA) and...
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