Article
Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle.
Scientific reports - 1 Jan 2011
Abbasi Amir Ali
Abstract excerpt
Hair is a unique mammalian trait that is absent in all other animal forms. Hairlessness is rare in mammals and humans are exceptional among primates in lacking dense layer of hair covering. HR was the first gene identified to be implicated in hair-cycle regulation. Point mutations in HR lead to congenital human hair loss, which results in the complete loss of body and scalp hairs. HR functions are indispensable...
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