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Article

Spinal muscular atrophy pathogenic mutations impair the axonogenic properties of axonal-survival of motor neuron.

Journal of neurochemistry - 1 May 2012

Locatelli Denise, d'Errico Paolo, Capra Silvia, Finardi Adele, Colciaghi Francesca, Setola Veronica, Terao Mineko, Garattini Enrico, Battaglia Giorgio

Abstract excerpt

The axonal survival of motor neuron (a-SMN) protein is a truncated isoform of SMN1, the spinal muscular atrophy (SMA) disease gene. a-SMN is selectively localized in axons and endowed with remarkable axonogenic properties. At present, the role of a-SMN in SMA is unknown. As a first step to verify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22324632
DOI: 10.1111/j.1471-4159.2012.07689.x

Genes

SMN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22324632-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Spinal muscular atrophy pathogenic mutations impair the axonogenic properties of axonal-survival of motor neuron.PMID 22324632Read ↗

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