Article
High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella typhimurium disease.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Apr 2012
Okoro Chinyere K, Kingsley Robert A, Quail Michael A, Kankwatira Anstead M, Feasey Nicholas A, Parkhill Julian, Dougan Gordon, Gordon Melita A
Abstract excerpt
BACKGROUND: Bloodstream infection with invasive nontyphoidal Salmonella (iNTS) is common and severe among human immunodeficiency virus (HIV)-infected adults throughout sub-Saharan Africa. The epidemiology of iNTS is poorly understood. Survivors frequently experience multiply recurrent iNTS disease, despite appropriate antimicrobial therapy, but recrudescence and reinfection have previously been difficult to...
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