Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host Cell Nucleolin Is Required To Maintain the Architecture of Human Cytomegalovirus Replication Compartments

8 Feb 2012

Abstract excerpt

UNLABELLED: Drastic reorganization of the nucleus is a hallmark of herpesvirus replication. This reorganization includes the formation of viral replication compartments, the subnuclear structures in which the viral DNA genome is replicated. The architecture of replication compartments is poorly understood. However, recent work with human cytomegalovirus (HCMV) showed that the viral DNA polymerase subunit UL44...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22318319
DOI: 10.1128/mbio.00301-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host Cell Nucleolin Is Required To Maintain the Architecture of Human Cytomegalovirus Replication CompartmentsPMID 22318319Read ↗

Nucleolin Associates with the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 and Is Necessary for Efficient Viral ReplicationSemantic proximity Read ↗

Human Cytomegalovirus UL44 Concentrates at the Periphery of Replication Compartments, the Site of Viral DNA SynthesisSemantic proximity Read ↗

Nucleolin Is Required for Efficient Nuclear Egress of Herpes Simplex Virus Type 1 NucleocapsidsSemantic proximity Read ↗

Identification of Human Cytomegalovirus Genes Important for Biogenesis of the Cytoplasmic Virion Assembly ComplexSemantic proximity Read ↗

The conserved N-terminal domain of herpes simplex virus 1 UL24 protein is sufficient to induce the spatial redistribution of nucleolinSemantic proximity Read ↗

The Human Cytomegalovirus UL97 Protein Kinase, an Antiviral Drug Target, Is Required at the Stage of Nuclear EgressSemantic proximity Read ↗

The Nucleolus and Its Interactions with Viral Proteins Required for Successful InfectionSemantic proximity Read ↗

Involvement of the nucleolus in replication of human virusesSemantic proximity Read ↗

Cellular v-ATPase is required for virion assembly compartment formation in human cytomegalovirus infectionSemantic proximity Read ↗

Conserved Residues in the UL24 Protein of Herpes Simplex Virus 1 Are Important for Dispersal of the Nucleolar Protein NucleolinSemantic proximity Read ↗

Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replicationSemantic proximity Read ↗

The dynamic organization of the perinucleolar compartment in the cell nucleus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.