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Article

Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice.

Cell research - 1 Apr 2012

Wang Yixuan, Zheng Chen-Guang, Jiang Yonghua, Zhang Jiqin, Chen Jiayu, Yao Chao, Zhao Qingguo, Liu Sheng, Chen Ke, Du Juan, Yang Ze, Gao Shaorong

Abstract excerpt

The generation of induced pluripotent stem cells (iPSCs) from differentiated somatic cells by over-expression of several transcription factors has the potential to cure many genetic and degenerative diseases currently recalcitrant to traditional clinical approaches. One such genetic disease is β-...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22310243
DOI: 10.1038/cr.2012.23
PMCID: PMC3317563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22310243-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice.PMID 22310243Read ↗

The Combination of CRISPR/Cas9 and iPSC Technologies in the Gene Therapy of Human β-thalassemia in Mice.Semantic proximity Read ↗

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Correction of Hemoglobin E/Beta-Thalassemia Patient-Derived iPSCs Using CRISPR/Cas9.Semantic proximity Read ↗

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