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Article

Functional characterization of genetic polymorphisms identified in the promoter region of the bovine PEPS gene.

DNA and cell biology - 1 Jun 2012

Ju Zhihua, Zheng Xue, Huang Jinming, Qi Chao, Zhang Yan, Li Jianbin, Zhong Jifeng, Wang Changfa

Abstract excerpt

Peptidase S (PEPS) is a metallopeptidase that cleaves N-terminal residues from proteins and peptides. PEPS is used as a cell maintenance enzyme with critical roles in peptide turnover. The promoter region located upstream of the initiation site plays an important role in regulating gene expression. Polymorphism in the promoter region can alter gene expression and lead to biological changes. In the current study,...

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PMID: 22304649
DOI: 10.1089/dna.2011.1555
PMCID: PMC3379527

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