Article
Low rates of nucleoside reverse transcriptase inhibitor resistance in a well-monitored cohort in South Africa on antiretroviral therapy.
Antiviral therapy - 1 Jan 2012
Wallis Carole L, Papathanasopolous Maria A, Fox Matthew, Conradie Francesca, Ive Prudence, Orrell Catherine, Zeinecker Jennifer, Sanne Ian, Wood Robin, McIntyre James, Stevens Wendy
Abstract excerpt
BACKGROUND: The emergence of complex HIV-1 drug resistance mutations has been linked to the duration of time patients are on a failing antiretroviral drug regimen. This study reports on resistance profiles in a closely monitored subtype C infected cohort. METHODS: A total of 812 participants were enrolled into the CIPRA-SA 'safeguard the household' study, viral loads were determined at 12-weekly intervals for 96...
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