Article
Proteomic analysis of the abomasal mucosal response following infection by the nematode, Haemonchus contortus, in genetically resistant and susceptible sheep.
Journal of proteomics - 3 Apr 2012
Nagaraj Shivashankar H, Harsha H C, Reverter Antonio, Colgrave Michelle L, Sharma Rakesh, Andronicos Nicholas, Hunt Peter, Menzies Moira, Lees Michael S, Sekhar Nirujogi R, Pandey Akhilesh, Ingham Aaron
Abstract excerpt
Sheep have a variable ability to resist gastrointestinal nematode infection, but the key factors mediating this response are poorly defined. Here we report the first large-scale application of quantitative proteomic technologies to define proteins that are differentially abundant between sheep selectively bred to have an enhanced (resistant) or reduced (susceptible) ability to eliminate nematodes. Samples were...
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