Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis

25 Jan 2012

Abstract excerpt

UNLABELLED: Hepatic stellate cell (HSC) activation is a pivotal event in initiation and progression of hepatic fibrosis and a major contributor to collagen deposition driven by transforming growth factor beta (TGF-β). MicroRNAs (miRs), small noncoding RNAs modulating messenger RNA (mRNA) and protein expression, have emerged as key regulatory molecules in chronic liver disease. We investigated differentially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Diseases and Immunity
Share to Liver physiology and pathology
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22278637
DOI: 10.1002/hep.25613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesisPMID 22278637Read ↗

Suppressive effect of microRNA‐29b on hepatic stellate cell activation and its crosstalk with TGF‐β1/Smad3Semantic proximity Read ↗

Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4.Semantic proximity Read ↗

MicroRNA‐19b Reduces Hepatic Stellate Cell Proliferation by Targeting GRB2 in Hepatic Fibrosis Models In Vivo and In Vitro as Part of the Inhibitory Effect of EstradiolSemantic proximity Read ↗

The role of miR-29a in the regulation, function, and signaling of liver fibrosisSemantic proximity Read ↗

The Role of miR-29a in the Regulation, Function, and Signaling of Liver FibrosisSemantic proximity Read ↗

Processing of miR17-92 Cluster in Hepatic Stellate Cells Promotes Hepatic Fibrogenesis During Alcohol-Induced InjurySemantic proximity Read ↗

Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarctionSemantic proximity Read ↗

Ferulic Acid Induces Bone Marrow Mesenchymal Stem Cells to Alleviate the Activation of Hepatic Stellate Cells and Liver Fibrosis via Cytoskeletal Rearrangement Inhibition and Mir-19b-3p TransferSemantic proximity Read ↗

microRNA are Central Players in Anti- and Profibrotic Gene Regulation during Liver FibrosisSemantic proximity Read ↗

Suppression of hepatic stellate cell activation by microRNA-29bSemantic proximity Read ↗

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosisSemantic proximity Read ↗

Exosome-Mediated Intercellular Communication between Hepatitis C Virus-Infected Hepatocytes and Hepatic Stellate CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.